COX-2 INHIBITORS AND CANCER RISK FACTORS

COX-2 inhibitors lower the risk of cancer in 2 major ways. They reduce inflammation and they block the COX-2 enzyme expression in tumors. As you learned above, inflammation creates copious amounts of oxygen free radicals and destroys natural tissue boundaries making it easier for tumors to grow. The COX-2 enzyme has a multitude of ways that it promotes the inception and cultivation of tumors. COX-2 enzyme inhibitors block every one of these tumor fostering processes.